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Updated: May 6, 2026

Optogenetic Manipulation of Neural Circuits During Monitoring Sleep/wakefulness States in Mice
Published on: June 19, 2019
Brain biology: jerked around by sleep
Jimmy J Fraigne1, John H Peever
1Department of Cell & Systems Biology, University of Toronto, Toronto, Ontario, M5S 3G5, Canada.
Abstract:
During rapid eye movement sleep, the forelimb muscles of newborn rats jerk and twitch in an organized pattern, the fidelity of which improves with time. The coordinated nature of such sleep movements may instruct the developing brain how to more effectively execute movements during wakefulness.
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