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False-positive rapid plasma reagin testing in patients with acute Plasmodium vivax malaria: a case control study
Ryan C Maves1, Katherine Dean2, Nilda Gadea3
1United States Naval Medical Research Unit No. 6, Lima, Peru; Division of Infectious Diseases, Department of Internal Medicine, Naval Medical Center San Diego, San Diego, CA, United States.
Abstract:
Non-treponemal tests such as the rapid plasma reagin (RPR) assay are mainstays of syphilis diagnosis, but false-positive tests are common. We identified false-positive RPR titers in 8.2% of patients with malaria due to Plasmodium vivax in northern Peru. Similar rates were not detected in patients with other acute febrile illnesses.
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