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Updated: May 6, 2026

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Biology of Microbial Communities - Interview
Published on: May 28, 2007
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Straight talk with... Ricardo Dolmetsch. Interview by Elie Dolgin
Nature Medicine
|November 9, 2013
Summary
Novartis is reviving its neuroscience division in Cambridge, MA, integrating stem cell technology. Ricardo Dolmetsch will lead efforts to advance brain disorder treatments, leveraging expertise in psychiatric genetics and induced pluripotent stem cells.
Area of Science:
- Neuroscience
- Biomedical Research
- Stem Cell Technology
Background:
- Novartis is restructuring its neuroscience research, relocating operations to Cambridge, Massachusetts.
- The new division aims to capitalize on the region's academic strengths in psychiatric genetics.
- The company previously announced plans to close its neuroscience operations in Basel, Switzerland.
Discussion:
- The appointment of Ricardo Dolmetsch as global head of neurosciences marks a significant step in the division's revival.
- Dolmetsch's background includes using induced pluripotent stem (iPS) cells to study Timothy syndrome, a rare form of autism.
- The integration of stem cell technologies is a key strategic focus for the reincarnated division.
Key Insights:
- Novartis is strategically investing in neuroscience drug development despite industry challenges.
- The company is leveraging advanced stem cell technologies for studying complex brain disorders.
- The Cambridge location provides access to a rich ecosystem of academic and biotech expertise.
Outlook:
- The new division aims to overcome historical challenges in neuroscience drug development.
- Integrating stem cell research may offer novel therapeutic approaches for neurological and psychiatric conditions.
- Future research will focus on translating stem cell findings into effective treatments for brain disorders.
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