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Updated: Jul 25, 2026

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Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents
Published on: September 16, 2020
Effect of oxygen tension on the quantities of procollagenase-activating angiogenic factor present in the developing
The British Journal of Ophthalmology
|March 1, 1986
Abstract:
Maintenance of newborn kittens in an oxygen rich atmosphere followed by a recovery period in a normal atmosphere mimicked the effects of the human disease retrolental fibroplasia. The retinas of such kittens contained significantly raised levels of low molecular weight angiogenic material (as measured by procollagenase activation) when compared with those of a control group of kittens.
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