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Related Experiment Video

Updated: May 6, 2026

Novel Object Recognition Test for the Investigation of Learning and Memory in Mice

Novel Object Recognition Test for the Investigation of Learning and Memory in Mice

Published on: August 30, 2017

Novelty assessment in the brain and long-term memory encoding.

E Tulving¹, N Kroll

¹University of California, Davis, California, tulving@psych.toronto.edu.

Psychonomic Bulletin & Review

|November 9, 2013

Summary

Novelty enhances memory encoding. New information is better remembered than familiar information due to brain novelty-assessment networks, supporting the novelty/encoding hypothesis.

Area of Science:

Neuroscience
Cognitive Psychology
Memory Research

Background:

Positron emission tomography (PET) studies reveal brain networks involved in novelty assessment.
The relationship between information novelty and memory encoding efficacy is not fully understood.

Purpose of the Study:

To test the "novelty/encoding" hypothesis.
To investigate if memory encoding depends on novelty as determined by brain networks.

Main Methods:

Subjects studied a list of words.
Words were categorized as novel (not previously encountered) or familiar (repeatedly presented).
Explicit recognition accuracy was measured.

Main Results:

Recognition accuracy was significantly higher for novel words compared to familiar words.

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Related Experiment Videos

Last Updated: May 6, 2026

Novel Object Recognition Test for the Investigation of Learning and Memory in Mice

Novel Object Recognition Test for the Investigation of Learning and Memory in Mice

Published on: August 30, 2017

Simultaneous Monitoring of Wireless Electrophysiology and Memory Behavioral Test as a Tool to Study Hippocampal Neurogenesis

Simultaneous Monitoring of Wireless Electrophysiology and Memory Behavioral Test as a Tool to Study Hippocampal Neurogenesis

Published on: August 20, 2020

Novel Object Recognition and Object Location Behavioral Testing in Mice on a Budget

Novel Object Recognition and Object Location Behavioral Testing in Mice on a Budget

Published on: November 20, 2018

Results support the prediction that novelty enhances memory encoding.

Conclusions:

Information novelty, assessed by brain networks, plays a crucial role in the efficacy of encoding information into long-term memory.
The findings support the "novelty/encoding" hypothesis, suggesting novel information is more readily encoded.