Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

849
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
849
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

955
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
955
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

548
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
548
Kidney Structure01:45

Kidney Structure

57.8K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
57.8K
Physiology of the Genitourinary System I: Renal Blood Flow and Glomerular Filtration01:29

Physiology of the Genitourinary System I: Renal Blood Flow and Glomerular Filtration

1.9K
The kidneys are vital organs responsible for regulating blood filtration, waste excretion, and fluid balance, all of which are crucial for maintaining homeostasis. Renal physiology examines renal blood flow, glomerular filtration, and urine formation, ensuring the body’s internal environment remains stable.Renal Blood FlowThe kidneys receive about 20-25% of the cardiac output, typically around 1200 mL of blood per minute in an average adult. Blood flows into the kidneys through the renal...
1.9K
Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

1.5K
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

OPTN/SRTR 2024 Annual Data Report: Deceased Organ Donation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2026
Same author

Corrigendum to OPTN/SRTR 2023 Annual Data Report: Introduction [American Journal of Transplantation. Volume 25, Issue 2, Supplement 1, February 2025, Pages S11-S21].

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2026
Same author

Changes in Organ Donation After Circulatory Death in the United States.

JAMA·2026
Same author

Hypothermic vs Normothermic Machine Perfusion in Liver Transplantation in the US: A Cohort Study.

Journal of the American College of Surgeons·2026
Same author

Promoting utilization of donors after circulatory death in lung transplantation.

JHLT open·2026
Same author

A Mycophenolate Pharmacokinetic Study with New Insights into Enterohepatic Recirculation in Kidney Transplant Recipients.

Clinical pharmacokinetics·2026

Related Experiment Video

Updated: May 6, 2026

Orthotopic Kidney Auto-Transplantation in a Porcine Model Using 24 Hours Organ Preservation And Continuous Telemetry
07:58

Orthotopic Kidney Auto-Transplantation in a Porcine Model Using 24 Hours Organ Preservation And Continuous Telemetry

Published on: August 21, 2020

7.3K

The kidney allocation system.

John J Friedewald1, Ciara J Samana, Bertram L Kasiske

  • 1Comprehensive Transplant Center, Department of Surgery, Feinberg School of Medicine, Northwestern University, 676 North Saint Clair Street, Suite 1900, Chicago, IL 60611, USA.

The Surgical Clinics of North America
|November 12, 2013
PubMed
Summary
This summary is machine-generated.

The current kidney allocation system needs an update. A new proposal better integrates highly sensitized patients and improves donor kidney matching, potentially increasing kidney transplant availability.

Keywords:
Kidney transplantOrgan allocationTransplant waiting list

More Related Videos

Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach
09:15

Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach

Published on: May 7, 2019

15.8K
Normothermic Machine Perfusion of Rat Kidneys for Transplantation
10:42

Normothermic Machine Perfusion of Rat Kidneys for Transplantation

Published on: January 27, 2026

857

Related Experiment Videos

Last Updated: May 6, 2026

Orthotopic Kidney Auto-Transplantation in a Porcine Model Using 24 Hours Organ Preservation And Continuous Telemetry
07:58

Orthotopic Kidney Auto-Transplantation in a Porcine Model Using 24 Hours Organ Preservation And Continuous Telemetry

Published on: August 21, 2020

7.3K
Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach
09:15

Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach

Published on: May 7, 2019

15.8K
Normothermic Machine Perfusion of Rat Kidneys for Transplantation
10:42

Normothermic Machine Perfusion of Rat Kidneys for Transplantation

Published on: January 27, 2026

857

Area of Science:

  • Nephrology
  • Transplantation immunology
  • Public health policy

Background:

  • The existing kidney allocation system is outdated and does not account for evolving patient demographics.
  • Current allocation methods may not optimally match donor kidneys to recipients, particularly for highly sensitized patients.

Purpose of the Study:

  • To propose a revised kidney allocation system that addresses deficiencies in the current model.
  • To incorporate the biological needs of highly sensitized patients into transplant waiting time algorithms.
  • To improve donor kidney longevity matching and recipient life expectancy.

Main Methods:

  • Development of a novel kidney allocation scoring algorithm.
  • Integration of biological data for highly sensitized patients.
  • Analysis of potential improvements in geographic sharing.

Main Results:

  • The proposed system aims to reduce mismatches between donor kidney viability and recipient life expectancy.
  • It offers incremental advancements towards greater geographic sharing of organs.
  • The system has the potential to increase the overall supply of viable donor kidneys.

Conclusions:

  • The proposed kidney allocation system represents a significant improvement over the current model.
  • It better accommodates the biological complexities of highly sensitized patients.
  • Implementation could lead to more equitable and effective kidney transplantation outcomes.