Analysis of endogenous and exogenous antigens in the nervous system using whole animal sections

We describe a method which uses protein blots of whole animal sections to map the distribution of exogenous and endogenous antigens to specific nuclei and tracts within the nervous system (NS). We propose this method as a new approach to analysis of the expression of NS gene products during development and to charting the course and molecular pathogenesis of infectious and immune disorders of the NS.