Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pain01:20

Pain

2.1K
Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
2.1K
Nociception01:44

Nociception

28.4K
Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain.
28.4K
Diencephalon: Thalamus and Information Relay01:27

Diencephalon: Thalamus and Information Relay

4.9K
The thalamus, often called “the gateway to the cerebral cortex,” is vital in processing and directing sensory and motor signals throughout the brain. Almost all inputs destined for the cerebral cortex, except for olfactory signals, are relayed through the thalamus. The thalamus is  a sophisticated relay station, channeling information from various brain regions to the cerebral cortex, as well as a filter, prioritizing certain signals over others based on current physiological...
4.9K
Thermosensation01:43

Thermosensation

29.7K
Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...
29.7K
Clamper Circuit01:14

Clamper Circuit

1.3K
A clamper circuit, also known as a DC restorer, represents a specialized variant of the rectifier circuit, notable for its method of taking the output across the diode rather than the capacitor. This configuration lends to several distinctive applications, particularly in handling square wave inputs.
Within this circuit, the diode's orientation prompts the capacitor to charge up to the level of the most negative peak of the input signal. Upon reaching this state, the diode ceases to...
1.3K
Ligand-gated Ion Channels01:19

Ligand-gated Ion Channels

11.4K
Ligand-gated ion channels are transmembrane proteins with a channel for ions to pass through and a binding site for a ligand. The channel opens only when a ligand attaches to the binding site.
Three Subfamilies of Ligand-gated Ion Channels
Ligand-gated ion channels fall into three subfamilies. The 'Cys-loop' includes the nicotinic acetylcholine receptors, γ-aminobutyric acid (GABA), glycine, and 5-hydroxytryptamine receptors. The second one is the 'Pore-loop' channels that...
11.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Atrial fibrillation detected after stroke: Recent advances and future directions.

International journal of stroke : official journal of the International Stroke Society·2026
Same author

Mechanism Attribution After Cryptogenic Stroke: Toward a RoPE Score for Atrial Fibrillation Detected After Stroke.

Stroke·2026
Same author

Early treatment of Atrial fibrillation for Stroke prevention Trial in acute STROKE (EAST-STROKE): protocol for an international investigator-initiated, prospective, randomised, open, blinded endpoint assessment (PROBE) interventional multi-centre trial.

European stroke journal·2026
Same author

Longitudinal evaluation of hippocampal subfields volumes and episodic memory in breast cancer patients and healthy controls.

Brain imaging and behavior·2026
Same author

Antithrombotic strategies for the secondary prevention of stroke: A review.

The American journal of medicine·2026
Same author

Integrating Digital Health Into Stroke Policies.

Stroke·2026

Related Experiment Video

Updated: May 6, 2026

Real-time Video Projection in an MRI for Characterization of Neural Correlates Associated with Mirror Therapy for Phantom Limb Pain
11:29

Real-time Video Projection in an MRI for Characterization of Neural Correlates Associated with Mirror Therapy for Phantom Limb Pain

Published on: April 20, 2019

9.2K

Thalamic cramplike pain.

Luciano A Sposato1, Harish A Sharma2, Ali R Khan2

  • 1Department of Clinical Neurological Sciences, London Health Sciences Centre, University of Western Ontario, London, ON, Canada.

Journal of the Neurological Sciences
|November 12, 2013
PubMed
Summary

Central post-stroke pain can manifest as thalamic cramplike pain. This study identifies specific neuroanatomical correlates in the thalamus linked to this debilitating condition.

Keywords:
CerebrovascularCrampsNeuroanatomyPainStrokeThalamusTopographyTractography

More Related Videos

Multi-Modal Signals for Analyzing Pain Responses to Thermal and Electrical Stimuli
09:16

Multi-Modal Signals for Analyzing Pain Responses to Thermal and Electrical Stimuli

Published on: April 5, 2019

11.4K
Author Spotlight: Insights into Remotely Supervised Neuromodulation Procedure for Phantom Limb Pain
06:13

Author Spotlight: Insights into Remotely Supervised Neuromodulation Procedure for Phantom Limb Pain

Published on: March 1, 2024

2.1K

Related Experiment Videos

Last Updated: May 6, 2026

Real-time Video Projection in an MRI for Characterization of Neural Correlates Associated with Mirror Therapy for Phantom Limb Pain
11:29

Real-time Video Projection in an MRI for Characterization of Neural Correlates Associated with Mirror Therapy for Phantom Limb Pain

Published on: April 20, 2019

9.2K
Multi-Modal Signals for Analyzing Pain Responses to Thermal and Electrical Stimuli
09:16

Multi-Modal Signals for Analyzing Pain Responses to Thermal and Electrical Stimuli

Published on: April 5, 2019

11.4K
Author Spotlight: Insights into Remotely Supervised Neuromodulation Procedure for Phantom Limb Pain
06:13

Author Spotlight: Insights into Remotely Supervised Neuromodulation Procedure for Phantom Limb Pain

Published on: March 1, 2024

2.1K

Area of Science:

  • Neurology
  • Neuroscience
  • Neuroimaging

Background:

  • Central post-stroke pain (CPSP) is a disabling neurological condition.
  • Thalamic pain syndrome is a recognized but often underdiagnosed form of CPSP.
  • Cramplike pain is a less common presentation of CPSP.

Observation:

  • A 68-year-old man presented with unilateral cramplike pain upon awakening.
  • Initial presentation mimicked musculoskeletal pain, delaying stroke diagnosis.
  • Diffusion-weighted MRI revealed an acute ischemic infarct in the left thalamus.

Findings:

  • The infarct was localized to the border of the pulvinar and ventral posterior medial nuclei.
  • Diffusion tensor tractography identified connections to Brodmann's areas 3, 1, 2, 4, and 6.
  • These areas include the primary somatosensory cortex and primary/secondary motor cortices.

Implications:

  • Thalamic cramplike pain should be recognized as a distinct type of CPSP.
  • Lesions in the pulvinar-ventral posterior border are implicated in this pain.
  • Understanding these neuroanatomical correlates may improve diagnosis and treatment of CPSP.