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Flavanone glycosides from Bidens gardneri Bak. (Asteraceae)
Denise Brentan Silva1, Laura Tiemi Okano, Norberto P Lopes
1Lychnoflora Pesquisa e Desenvolvimento em Produtos Naturais LTDA, Campus USP, Ribeirão Preto, SP, Brazil; Núcleo de Pesquisa em Produtos Naturais e Sintéticos (NPPNS), Faculdade de Ciências Farmacêuticas de Ribeirão Preto - Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Abstract:
LC-DAD-MS/MS analysis of the Brazilian medicinal plant Bidens gardneri Bak. (Asteraceae) results in identification of eleven phenolic compounds. HRESIMS, MS/MS and UV data analyses, with phytochemicals isolation guided by MS data, results in flavanones-(-)-4'-methoxy-7-O-β-D-glucopyranosyl-8,3'-dihydroxyflavanone; (-)-7-O-(6″-E-p-coumaroyl)-β-D-glucopyranosyl-8,3',4'-trihydroxyflavanone; and (-)-4'-methoxy-7-O-(6″-acetyl)-β-D-glucopyranosyl-8,3'-dihydroxyflavanone being identified-together with four known compounds. The absolute configurations of two of the flavanones were determined as 2S via circular dichroism.
