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Prostate MRI: can we do without DCE sequences in 2013?

P Puech1, A Sufana-Iancu, B Renard

  • 1Department of Uroradiology, Lille Hospital, 1, rue Michel-Polonovski, 59037 Lille cedex, France; University of Lille Nord de France, Lille 59800, France; Inserm U703, 59120 Loos, France.

Diagnostic and Interventional Imaging
|November 12, 2013
PubMed

Insights

Dynamic contrast-enhanced (DCE) MRI sequences for prostate cancer detection are debated. While potentially redundant, they offer unique insights into lesion visibility, cancer staging, and recurrence detection, crucial for treatment decisions.

Area of Science:

  • Radiology
  • Oncology
  • Medical Imaging

Background:

  • Multiparametric MRI (mp-MRI) is a stable tool for prostate cancer assessment.
  • Dynamic contrast-enhanced (DCE) sequences in mp-MRI are under scrutiny due to potential redundancy with diffusion-weighted imaging (DWI) and contrast agent costs.

Purpose of the Study:

  • To evaluate the role and necessity of DCE sequences within current prostate MRI protocols.
  • To discuss the implications of omitting DCE sequences for prostate cancer diagnosis and management.

Main Methods:

  • Review of existing literature on the applications of dynamic MRI in prostate cancer.
  • Analysis of the unique contributions of DCE sequences compared to T2-weighted and DWI sequences.
  • Discussion of the impact of DCE sequence omission on clinical practice.

Main Results:

  • DCE sequences can identify lesions not visible on T2-weighted and DWI.
  • These sequences improve the assessment of prostate cancer extent and aggressiveness.
  • DCE MRI aids in detecting post-treatment recurrence.

Conclusions:

  • Despite challenges, DCE sequences provide valuable, unique information in prostate MRI.
  • Omitting DCE sequences may hinder comprehensive cancer evaluation and recurrence detection.
  • Careful consideration is needed before removing DCE from prostate MRI protocols.
Keywords:
CancerDiffusion-weighted-imaging (DWI)Perfusion (DCE-MRI)Prostate

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