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Updated: May 6, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Vitamin K status in chronic kidney disease
Kristin M McCabe1, Michael A Adams, Rachel M Holden
1Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON K7L 3V6, Canada. holdenr@kgh.kari.net.
Abstract:
The purpose of this review is to summarize the research to date on vitamin K status in chronic kidney disease (CKD). This review includes a summary of the data available on vitamin K status in patients across the spectrum of CKD as well as the link between vitamin K deficiency in CKD and bone dynamics, including mineralization and demineralization, as well as ectopic mineralization. It also describes two current clinical trials that are underway evaluating vitamin K treatment in CKD patients. These data may inform future clinical practice in this population.
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