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Improving 2D and 3D Skin In Vitro Models Using Macromolecular Crowding
Published on: August 22, 2016
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When crowding of crowding leads to uncrowding
Mauro Manassi1, Bilge Sayim, Michael H Herzog
1Laboratory of Psychophysics, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Journal of Vision
|November 12, 2013
Summary
Figural processing influences low-level vision, challenging hierarchical models. Adding more shapes surprisingly reduced crowding, suggesting complex interactions precede basic feature analysis in object recognition.
Area of Science:
- Visual perception
- Cognitive neuroscience
- Computational vision
Background:
- Object recognition is traditionally viewed as hierarchical, processing from simple features to complex objects.
- Current models suggest low-level visual analysis precedes higher-level figural processing.
Purpose of the Study:
- To investigate the influence of figural processing on low-level visual analysis.
- To challenge the prevailing hierarchical model of object recognition.
Main Methods:
- Utilizing Vernier offset discrimination tasks.
- Employing visual crowding paradigms with single and multiple squares.
- Analyzing the impact of contextual elements on feature discrimination.
Main Results:
- Vernier offset discrimination significantly worsened when a Vernier was presented within a single square (crowding effect).
- Crowding effects were unexpectedly reduced when additional squares were introduced.
- These findings indicate that higher-level figural interactions can modulate low-level processing.
Conclusions:
- Figural processing appears to precede and influence low-level visual analysis, contrary to hierarchical models.
- The interaction between multiple contextual elements (squares) alters the suppression of target features (Vernier).
- This suggests a more dynamic and interactive visual processing system than previously assumed.
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