Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Corpus cavernosum autoinjection therapy: initial experiences in erectile dysfunction].

C G Stief, W Bähren, H Gall

    Der Urologe. Ausg. A
    |January 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Dynamic phenotypic shifts and M2 receptor downregulation in bladder smooth muscle cells induced by mirabegron.

    Frontiers in pharmacology·2024
    Same author

    [Urinary diversion for acute epididymitis : Transurethral or suprapubic catheter?]

    Urologie (Heidelberg, Germany)·2022
    Same author

    [Enhanced Recovery After Surgery (ERAS®) after radical cystectomy-current data].

    Der Urologe. Ausg. A·2021
    Same author

    <sup>18</sup>F-PSMA-1007 PET/CT for response assessment in patients with metastatic renal cell carcinoma undergoing tyrosine kinase or checkpoint inhibitor therapy: preliminary results.

    European journal of nuclear medicine and molecular imaging·2020
    Same author

    [The role of the microbiome in urology].

    Der Urologe. Ausg. A·2020
    Same author

    [The microbiome in benign prostatic hyperplasia].

    Der Urologe. Ausg. A·2020
    Same journal

    Der Urologe. Ausg. A·2022
    Same journal

    Der Urologe. Ausg. A·2022
    Same journal

    Der Urologe. Ausg. A·2022
    Same journal

    Der Urologe. Ausg. A·2022
    Same journal

    Der Urologe. Ausg. A·2022
    Same journal

    Der Urologe. Ausg. A·2022
    See all related articles

    Self-injection therapy using phentolamine and papaverine hydrochloride effectively treated most men with vasculogenic erectile dysfunction. This treatment, called cavernosal auto-injection therapy (CCAT), showed high success rates with manageable side effects.

    Area of Science:

    • Urology
    • Andrology
    • Pharmacology

    Context:

    • Erectile dysfunction (ED) affects a significant number of men, impacting quality of life.
    • Vasculogenic ED, a common form, necessitates effective therapeutic strategies.
    • A multidisciplinary approach is often required for comprehensive ED evaluation.

    Purpose:

    • To evaluate the efficacy and safety of cavernosal auto-injection therapy (CCAT) for treating vasculogenic erectile dysfunction.
    • To determine optimal individual dosages for phentolamine mesylate-papaverine hydrochloride injections.
    • To assess patient adherence and outcomes with home-based CCAT.

    Summary:

    • A study involved 120 impotent patients, with 20 diagnosed with vasculogenic ED offered CCAT.
    • Nineteen patients accepted CCAT, receiving individualized phentolamine-papaverine hydrochloride injections.

    Related Experiment Videos

  • Eighteen patients successfully self-administered the therapy at home; prolonged erections in 2 were managed by corpus puncture without therapy discontinuation. CCAT failed in one patient with severe venous leak.

    • Impact:

    • CCAT presents a viable and effective treatment option for men with vasculogenic erectile dysfunction.
    • Individualized dosing and patient education are key to successful self-injection therapy.
    • Understanding potential side effects and their management is crucial for patient safety and treatment continuation.