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Post-operative cyclizine misuse.

J Woodfield1, E J St George

  • 1Neurosurgery Specialty Trainee, Institute of Neurological Sciences, Southern General Hospital, UK.

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|November 12, 2013
PubMed
Summary
This summary is machine-generated.

This study reports the first case of postoperative addiction to intravenous cyclizine, an anti-emetic drug, administered at recommended doses. Healthcare providers should recognize cyclizine

Keywords:
Cyclizineanti-emeticssubstance abuse

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Area of Science:

  • Pharmacology
  • Addiction Medicine
  • Clinical Case Reports

Background:

  • Cyclizine is a widely used anti-emetic medication, particularly for postoperative nausea and vomiting.
  • While generally considered safe at recommended doses, the potential for misuse and addiction is not well-documented.

Observation:

  • A case report details a 51-year-old woman who developed addiction to intravenous cyclizine.
  • The addiction occurred despite regular administration at recommended therapeutic doses.
  • This represents the first documented instance of post-operative cyclizine misuse.

Findings:

  • The patient exhibited addictive behaviors related to intravenous cyclizine use.
  • This case highlights a previously unreported route of cyclizine abuse.
  • Comparison with other populations reveals shared patterns of substance misuse.

Implications:

  • Clinicians must be vigilant regarding the potential for cyclizine to be a drug of abuse, even when prescribed appropriately.
  • Awareness of cyclizine's addictive potential is crucial for post-operative care and patient monitoring.
  • Further research may be warranted to understand the mechanisms and prevalence of cyclizine addiction.