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Related Experiment Video

Updated: May 6, 2026

Preparation and Using Phantom Lesions to Practice Fine Needle Aspiration Biopsies
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Pitfalls in EUS FNA.

Larissa L Fujii1, Michael J Levy

  • 1Division of Gastroenterology and Hepatology, Mayo Clinic, 200 1st Street Southwest, Rochester, MN 55905, USA.

Gastrointestinal Endoscopy Clinics of North America
|November 13, 2013
PubMed
Summary

Endoscopic ultrasound (EUS) fine-needle aspiration (FNA) is a safe diagnostic tool, but its accuracy can be improved. Optimizing EUS FNA involves careful technique and interpretation to maximize diagnostic yield and patient safety.

Keywords:
CytopathologyDiagnostic yieldEndosonographyFine-needle aspirationLimitation

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Area of Science:

  • Gastroenterology
  • Interventional Endoscopy
  • Cytopathology

Background:

  • Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a valuable diagnostic procedure.
  • The diagnostic yield of EUS-FNA can be variable despite its safety and accuracy.

Purpose of the Study:

  • To identify factors influencing the diagnostic accuracy of EUS-FNA.
  • To discuss potential pitfalls and strategies for optimization of EUS-FNA procedures.

Main Methods:

  • Review of factors affecting EUS-FNA performance and interpretation.
  • Discussion of best practices for specimen collection, handling, and ancillary techniques.

Main Results:

  • Diagnostic accuracy is influenced by endosonographer and cytopathologist expertise, image quality, lesion targeting, and specimen handling.
  • Errors in judgment or technique at any stage can compromise results.

Conclusions:

  • Optimizing EUS-FNA requires meticulous attention to detail throughout the procedure, from targeting to interpretation.
  • Adherence to best practices can enhance the diagnostic yield, efficiency, and safety of EUS-FNA.