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Drug Metabolism: Phase II Reactions01:14

Drug Metabolism: Phase II Reactions

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Phase II reactions are essential for the detoxification and elimination of drugs from the body. These reactions involve the conjugation of parent drugs or their phase I metabolites with endogenous molecules, resulting in more hydrophilic drug conjugates. The primary conjugation reactions in this phase are sulfation and glucuronidation. Both sulfation and glucuronidation typically produce biologically inactive metabolites. However, in some cases involving prodrugs, active metabolites may be...
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A Reporter Assay to Analyze Intronic microRNA Maturation in Mammalian Cells
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Reply: To PMID 23790348

Larissa R Brunner Huber1, Jordan E Lyerly1, Katie E Farley1

  • 1Department of Public Health Sciences, University of North Carolina Charlotte, NC, USA.

Annals of Epidemiology
|November 13, 2013
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No abstract available in PubMed .

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