Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Chromatix: a differentiable, GPU-accelerated wave-optics library.

Nature methods·2026

Same author

Chromatix: a differentiable, GPU-accelerated wave-optics library.

bioRxiv : the preprint server for biology·2026

Same author

Morphological artifacts in pulmonary pathology and literature review.

Virchows Archiv : an international journal of pathology·2026

Same author

Hybrid particle-wave Monte Carlo OCT simulation method provides a three orders of magnitude improvement in efficiency.

Biomedical optics express·2026

Same author

Dual-parameter tomographic imaging of attenuation and backscattering coefficients for quantitative evaluation of immune cell-mediated cytotoxicity in tumor spheroids.

Theranostics·2025

Same author

Oblique Light Sheet Fluorescence Microscopy With Surface Tracking for High-Speed Large-Area Imaging of Conjunctival Goblet Cells.

IEEE transactions on medical imaging·2025

Same journal

Multifunctional reconfigurable terahertz metasurface based on vanadium dioxide phase transition: achieving broadband absorption and efficient polarization conversion.

Applied optics·2026

Same journal

High-Q-factor electromagnetically induced transparency utilizing quasi-bound states in the continuum in an all-dielectric terahertz metasurface.

Applied optics·2026

Same journal

Automated stitching interferometry for high-precision metrology of X-ray mirrors.

Applied optics·2026

Same journal

Experimental demonstration of an approach to designing a metal-dielectric DBR resonant cavity structure.

Applied optics·2026

Same journal

High-precision wavefront reconstruction from a single-shot interferogram using a physics-driven hybrid feature calibration network.

Applied optics·2026

Same journal

Ultra-high-Q Fano resonance based on coupled topological corner states in Kagome photonic crystals.

Applied optics·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 6, 2026

Measurement of Particle Size Distribution in Turbid Solutions by Dynamic Light Scattering Microscopy

Measurement of Particle Size Distribution in Turbid Solutions by Dynamic Light Scattering Microscopy

Published on: January 9, 2017

Field-based dynamic light scattering microscopy: theory and numerical analysis.

Chulmin Joo, Johannes F de Boer

|November 13, 2013

Summary

This summary is machine-generated.

We developed a theoretical framework for field-based dynamic light scattering microscopy using spectral-domain optical coherence phase microscopy. This method measures localized sample dynamics with high spatial resolution, offering insights into diffusive and directional properties.

More Related Videos

Controlled Synthesis and Fluorescence Tracking of Highly Uniform PolyN-isopropylacrylamide Microgels

Controlled Synthesis and Fluorescence Tracking of Highly Uniform PolyN-isopropylacrylamide Microgels

Published on: September 8, 2016

An Analog Macroscopic Technique for Studying Molecular Hydrodynamic Processes in Dense Gases and Liquids

An Analog Macroscopic Technique for Studying Molecular Hydrodynamic Processes in Dense Gases and Liquids

Published on: December 4, 2017

Related Experiment Videos

Last Updated: May 6, 2026

Measurement of Particle Size Distribution in Turbid Solutions by Dynamic Light Scattering Microscopy

Measurement of Particle Size Distribution in Turbid Solutions by Dynamic Light Scattering Microscopy

Published on: January 9, 2017

Controlled Synthesis and Fluorescence Tracking of Highly Uniform PolyN-isopropylacrylamide Microgels

Controlled Synthesis and Fluorescence Tracking of Highly Uniform PolyN-isopropylacrylamide Microgels

Published on: September 8, 2016

An Analog Macroscopic Technique for Studying Molecular Hydrodynamic Processes in Dense Gases and Liquids

An Analog Macroscopic Technique for Studying Molecular Hydrodynamic Processes in Dense Gases and Liquids

Published on: December 4, 2017

Area of Science:

Biophysics
Optical Microscopy
Photonics

Background:

Spectral-domain optical coherence phase microscopy (SD-OCPM) enables quantitative measurement of scattered light amplitude and phase with high stability.
Field-based dynamic light scattering (F-DLS) analysis provides direct evaluation of the complex-valued field autocorrelation function.

Purpose of the Study:

To establish a theoretical framework for field-based dynamic light scattering microscopy on an SD-OCPM platform.
To investigate the influence of imaging optics' numerical aperture on F-DLS measurements.
To enable localized measurement of diffusive and directional dynamics in biological and material samples.

Main Methods:

Development of a theoretical framework for F-DLS microscopy.
Utilizing a spectral-domain optical coherence phase microscopy (SD-OCPM) platform.
Performing theoretical and numerical analyses to evaluate the effect of numerical aperture.

Main Results:

Demonstrated that sharp focusing of fields impacts measured diffusive and transport velocity.
Observed that focusing effects lead to underestimation of sample dynamic properties.
Identified the influence of numerical aperture on the accuracy of dynamic property measurements.

Conclusions:

The theoretical framework provides insight into F-DLS microscopy data interpretation.
Accurate determination of sample dynamic properties requires consideration of focusing effects.
This approach enhances the capability for high-resolution analysis of localized sample dynamics.