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Updated: May 6, 2026

Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
Published on: July 21, 2011
VX and VG chemical warfare agents bidentate complexation with lanthanide ions
Genevieve H Dennison1, Mark R Sambrook, Martin R Johnston
1Human Protection and Performance Division, Defence Science and Technology Organisation, Fishermans Bend, Melbourne, Australia. genevieve.dennison@dsto.defence.gov.au genevieve.dennison@flinders.edu.au.
Abstract:
Investigations into V-agent interaction with 1,10-phenanthroline nitrate Ln(III) complexes (Eu and Tb) were carried out using luminescence and UV-Vis spectroscopy. Addition of several equivalents of agent resulted in the loss of luminescence intensity and the observation of free 1,10-phenanthroline by UV-Vis. We propose a displacement mechanism in which the V-agent acts as a bidentate ligand to the lanthanide ion. Association constants were determined by luminescence titrations and found to be 10(5) mol(-1) dm(3).
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