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Updated: May 6, 2026

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
Published on: April 28, 2022
[Predictors of success of long-term treatment in alcohol dependency]
E Grau1, D Kemmann1, P Brieger2
1Rehabilitationsklinik für Suchterkrankungen, Diakonie-Krankenhaus Harz, Elbingerode.
Objective:
There is a lack of positive predictors for long-term treatment of subjects with alcohol addiction. We analyzed the relation between motivation and other external variables of access to treatment as well as treatment outcome.
Method:
434 persons with alcohol addiction, treated in 2004 in the Diakonie-Krankenhaus Harz (DHK), Elbingerode, as part of a long-term therapy, were followed-up one year after treatment. Access variables were defined and examined in relation to outcome variables with multiple linear and logistic regressions.
Result:
Ways of accessing treatment had no effect on later treatment outcome, while motivation at the start of therapy was relevant: Patients with ambivalent motivation had the most negative outcome.
Conclusion:
Therapy motivation was the main predictor for the outcome of a long-term anti-addiction treatment. To improve the quality of the treatment system, interventions to strengthen motivation should be promoted.
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