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Oral foregut cyst in a neonate

Ana Cláudia Garcia Rosa1, Daniel Martins Hiramatsu, Fábio Roberto Ruiz de Moraes

  • 1From the *Federal University of Tocantins, Palmas, Tocantins, †São Leopoldo Mandic Institute and Research Center, Campinas, São Paulo; ‡General Public Hospital of Palmas; and §Dona Regina Public Maternity Hospital, Palmas, Tocantins, Brazil.

The Journal of Craniofacial Surgery
|November 14, 2013
PubMed

Insights

This study reports a rare case of a large congenital oral foregut cyst in a neonate that hindered breastfeeding. Surgical removal led to successful healing and restoration of feeding, with no recurrence.

Area of Science:

  • Developmental biology
  • Pediatric surgery
  • Oral pathology

Background:

  • Oral foregut cysts are rare congenital tumors originating from embryonic foregut epithelium.
  • They can present as cystic lesions in the oral cavity, potentially causing feeding difficulties in neonates.

Observation:

  • A neonate presented with a large sublingual cystic lesion affecting the tongue and floor of mouth, impeding breastfeeding.
  • Differential diagnoses included dermoid cyst, epidermoid cyst, mucous retention cyst, and oral lymphangioma.

Findings:

  • Histological examination revealed a cystic lesion with ciliated pseudostratified columnar epithelium and goblet cells.
  • Immunohistochemistry confirmed the diagnosis of oral foregut cyst, showing positivity for cytokeratin 7 and thyroid transcription factor 1.

Implications:

  • Enucleation under general anesthesia is an effective treatment for congenital oral foregut cysts.
  • Early diagnosis and surgical intervention can resolve feeding issues and prevent long-term complications.

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