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Postradiation sarcoma from a free flap
Ugur Anil Bingol1, Hakan Arslan, Can Cinar
1From the *Department of Plastic, Reconstructive and Aesthetic Surgery, Yeditepe Medical School, Yeditepe University; and †Department of Plastic, Reconstructive and Aesthetic Surgery, Cerrahpaşa Medical School, Istanbul University, Istanbul, Turkey.
The Journal of Craniofacial Surgery
|November 14, 2013
Summary
Post-radiation sarcomas are rare but can develop years after radiotherapy (RT). This case highlights a leiomyosarcoma originating from a free muscle flap, emphasizing the need for long-term patient monitoring after RT.
Area of Science:
- Oncology
- Surgical Reconstruction
- Radiation Oncology
Background:
- Postradiation sarcomas are rare, high-grade tumors developing 3-20 years after radiotherapy (RT).
- Common types include osteosarcomas, fibrosarcomas, and leiomyosarcomas.
- Originating from free flaps is exceptionally uncommon.
Observation:
- A patient developed a mass in the upper jaw 10 years after RT for ethmoid sinus cancer.
- Reconstruction involved a rectus abdominis free muscle flap.
- Imaging revealed the mass originated from the free muscle flap.
Findings:
- Biopsy confirmed a malignant mesenchymal tumor.
- Pathology identified leiomyosarcoma with bone invasion.
- Surgical resection included the free flap and maxillectomy.
Implications:
- Increased life expectancy necessitates long-term surveillance for RT patients.
- Early diagnosis and complete resection are crucial for survival.
- Clinicians must remain vigilant for late-developing sarcomas post-RT.

