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Updated: May 6, 2026

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
Tourniquet used in anterior cruciate ligament reconstruction: a system review
Hong Wu1, Ling-Xiao Chen, Yu-Lin Li
1Department of Orthopaedics, Tianjin Medical University, General Hospital, 154 Anshan Road, Heping District, Tianjin, 300052, People's Republic of China.
Purpose:
To identify whether routine use of a tourniquet is a better choice for anterior cruciate ligament reconstruction.
Method:
We searched Amed, British Nursing Index, Embase, Pubmed, Scopus, Cochrane Library and Google Scholar. We used revised Jadad score to evaluate the trial quality. Each reference list was viewed for any ignored studies. Two reviews independently extracted data from all eligible trials, including study design, patients' characteristics, interventions and outcomes. The available data were using random effects models with mean differences for continuous variables.
Results:
The only meta-analysis indicated there was no significant difference in operative time between the tourniquet and non-tourniquet groups (mean differences -5.71, 95 % CI -12.40, 0.99). The remaining outcomes had variations in the outcome measures, so it was not possible to perform meta-analysis.
Conclusions:
There was insufficient evidence to support the hypothesis that patients would benefit from routinely applying a tourniquet. More high-quality randomized controlled trials were needed to test the result.
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