Rhabdomyolysis induced by excessive coffee drinking
W-F Chiang1, M-T Liao2, C-J Cheng3
1Department of Medicine, Armed Forces Taoyuan General Hospital, Taoyuan, Taiwan Division of Nephrology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Human & Experimental Toxicology
|November 14, 2013
Summary
Excessive caffeine intake can cause rhabdomyolysis, a rare condition where muscle fibers break down. This case highlights the potential health risks of consuming large amounts of caffeine-containing beverages.
Area of Science:
- Toxicology
- Nephrology
- Neurology
Background:
- Caffeine is a widely consumed stimulant found in beverages like coffee and tea.
- Excessive caffeine intake is rarely associated with severe health consequences.
- Rhabdomyolysis is a condition characterized by muscle breakdown and the release of myoglobin into the bloodstream.
Observation:
- A 44-year-old woman developed nausea, vomiting, palpitations, and tea-colored urine after drinking 1 liter of black coffee (approx. 565 mg caffeine).
- She presented with symptoms consistent with rhabdomyolysis, including myoglobinuria and significantly elevated plasma creatine kinase (CK) levels (7315 U/L).
Findings:
- The patient's condition was successfully treated with volume expansion and alkalization.
- Plasma CK levels normalized within 5 days, indicating recovery from rhabdomyolysis.
Implications:
- This case underscores that excessive consumption of caffeine-containing products can pose a significant health hazard.
- Rhabdomyolysis should be considered in the differential diagnosis for patients presenting with symptoms after high caffeine intake.
- Awareness of caffeine's potential toxicity is crucial for both healthcare providers and consumers.
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