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Enhanced visualization of the choroido-scleral interface using swept-source OCT.

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    A new swept-source optical coherence tomography (SS-OCT) system effectively visualizes the choroido-scleral interface, crucial for analyzing choroidal thickness in eye diseases. This technology surpasses spectral-domain OCT (SD-OCT) in visualization success rates.

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    Area of Science:

    • Ophthalmology
    • Medical Imaging
    • Retinal Imaging

    Background:

    • Accurate choroidal thickness analysis relies on visualizing the choroido-scleral interface.
    • Spectral-domain optical coherence tomography (SD-OCT) systems show variable success in visualizing this interface.

    Purpose of the Study:

    • To compare the visualization of the choroido-scleral interface using spectral-domain OCT (SD-OCT) with and without enhanced depth imaging (EDI) versus a prototype long-wavelength swept-source OCT (SS-OCT) system.
    • To assess the clinical utility of SS-OCT for evaluating choroidal diseases.

    Main Methods:

    • Prospective study involving 19 healthy participants (19 eyes).
    • High-definition raster scanning performed with SD-OCT (with and without EDI) and a prototype long-wavelength SS-OCT.
    • Comparison of choroido-scleral interface visualization rates between the imaging systems.

    Main Results:

    • The SS-OCT system visualized the choroido-scleral interface in 100% of eyes.
    • SD-OCT without EDI visualized the interface in 68.4% of eyes (P = .009).
    • SD-OCT with EDI visualized the interface in 73.6% of eyes (P = .02).

    Conclusions:

    • The prototype long-wavelength SS-OCT system demonstrates superior visualization of the choroido-scleral interface compared to SD-OCT.
    • The enhanced visualization capabilities, speed, and penetration of SS-OCT suggest significant clinical utility for diagnosing chorioretinal diseases.