Related Experiment Video
Updated: May 6, 2026
Animal Model of Implant-Associated Infections in Mice
Published on: June 27, 2025
Mouse model of post-arthroplasty Staphylococcus epidermidis joint infection
Tyler D Scherr1, Kevin E Lindgren, Carolyn R Schaeffer
1Department of Pathology and Microbiology, Center for Staphylococcal Research, University of Nebraska Medical Center, Omaha, NE, USA.
Abstract:
Animal models are invaluable tools for translational research, allowing investigators to recapitulate observed clinical scenarios within the laboratory that share attributes with human disease. Here, we describe a mouse model of post-arthroplasty Staphylococcus epidermidis joint infection which mimics human disease and may be utilized to explore the complex series of events during staphylococcal implant-associated infections by identifying key immunological, bacterial, and/or therapeutic mechanisms relevant to these persistent infections.
