Related Experiment Video
Updated: May 6, 2026
10:04
Enhancing Tumor Content through Tumor Macrodissection
Published on: February 12, 2022
14.3K
Primary ovarian large B-cell lymphoma
Mine Islimye Taskın1, Levent Gokgozoglu, Bedrı Kandemır
1Department of Obstetrics and Gynecology, Balıkesir University School of Medicine, Balikesir, Turkey.
Case Reports in Obstetrics and Gynecology
|November 14, 2013
Summary
Primary ovarian lymphoma, a rare condition, was diagnosed in a 38-year-old woman. Treatment with R-CHOP chemotherapy resulted in a 24-month cancer-free survival, highlighting successful management of this uncommon lymphoma presentation.
Area of Science:
- Oncology
- Hematology
- Gynecologic Oncology
Background:
- Malignant lymphoma rarely involves the ovary, typically as a late sign of widespread nodal disease.
- Primary ovarian lymphoma is an exceptionally rare clinical presentation.
Purpose of the Study:
- To report a rare case of primary ovarian diffuse large B-cell lymphoma.
- To describe the diagnostic and therapeutic approach for this uncommon entity.
Main Methods:
- Case presentation of a 38-year-old woman with incidentally detected unilateral ovarian mass.
- Preoperative imaging (ultrasound) and surgical intervention (salpingo-oophorectomy).
- Postoperative diagnosis confirmed by immunostaining and treatment with R-CHOP regimen.
Main Results:
- Incidental detection of a 46x42 mm heterogeneous cystic mass in the left ovary.
- Histopathological diagnosis of diffuse large B-cell lymphoma after immunostaining.
- Successful treatment with R-CHOP chemotherapy, with the patient remaining cancer-free for 24 months.
Conclusions:
- Primary ovarian diffuse large B-cell lymphoma is a rare but manageable condition.
- Multidisciplinary approach involving surgery and chemotherapy is crucial for successful outcomes.
- Early diagnosis and prompt treatment can lead to favorable prognosis in primary ovarian lymphoma.
Related Concept Videos
01:27Ovarian Cycle
5.5K
The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle...
5.5K
01:16Primary Lymphoid Organs
9.6K
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
9.6K
01:20Folliculogenesis
3.8K
Folliculogenesis is the development of ovarian follicles, the specialized structures within the ovarian cortex where oogenesis, or egg development, occurs. This process is essential for female reproductive health and begins during fetal development when primordial follicles are formed. Each primordial follicle comprises a primary oocyte in the center, surrounded by a single layer of squamous pre-granulosa cells. These follicles remain dormant in late prophase I of meiosis until triggered by...
3.8K
01:15Secondary Lymphoid Organs
7.3K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
7.3K
02:07Oogenesis
58.5K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
58.5K
01:22Oogenesis
5.1K
Oogenesis, the process of developing egg cells (female gametes), occurs within the ovaries and is fundamental to female fertility. This sequence begins during fetal development when diploid oogonia in the developing ovaries undergo mitotic divisions to produce primary oocytes. By birth, these primary oocytes enter prophase I of meiosis but become arrested in this stage, remaining suspended until puberty.
Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is...
Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is...
5.1K