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Reexpansion pulmonary edema: review of pediatric cases
1Division of Anesthesia, Medical Department, Beppu Developmental Medicine & Rehabilitation Center, Beppu, Japan.
Insights
Reexpansion pulmonary edema (RPE) can affect children of all ages after lung reexpansion. Awareness and prompt intervention are crucial for managing this rare but potentially severe condition in pediatric patients.
Area of Science:
- Pulmonology
- Pediatric Medicine
- Critical Care
Background:
- Reexpansion pulmonary edema (RPE) is a rare complication following lung reexpansion.
- While RPE is known to affect younger adults, pediatric cases lack detailed analysis.
- Understanding RPE in children is crucial for timely diagnosis and management.
Purpose of the Study:
- To review and analyze reported pediatric cases of reexpansion pulmonary edema.
- To identify characteristics, outcomes, and potential risk factors in pediatric RPE.
- To inform pediatricians and anesthesiologists about this condition.
Main Methods:
- PubMed literature search using specific keywords for pediatric RPE.
- Inclusion of all identified pediatric cases of RPE.
- Analysis of case characteristics, clinical features, and treatment approaches.
Main Results:
- Twenty-two pediatric cases of RPE were identified across a wide age range.
- RPE severity varied from subclinical to lethal.
- Ten cases occurred during the perioperative period, unrelated to specific procedures or anesthetic techniques.
Conclusions:
- Pediatric RPE can occur after reexpansion of any collapsed lung.
- No specific treatment for RPE was identified; management is based on clinical presentation.
- Pediatric anesthesiologists must be aware of RPE and consider invasive therapies for severe cases.
Abstract:
Reexpansion pulmonary edema (RPE) is an increased permeability pulmonary edema that usually occurs in the reexpanded lung after several days of lung collapse. This condition is recognized to occur more frequently in patients under the age of 40 years, but there has been no detailed analysis of reported pediatric cases of RPE to date. For this review, PubMed literature searches were performed using the following terms: 're(-)expansion pulmonary (o)edema' AND ('child' OR 'children' OR 'infant' OR 'boy' OR 'girl' OR 'adolescent'). The 22 pediatric cases of RPE identified were included in this review. RPE was reported in almost the entire pediatric age range, and as in adult cases, the severity ranged from subclinical to lethal. No specific treatment for RPE was identified, and treatment was administered according to the clinical features of each patient. Of the 22 reported cases, 10 occurred during the perioperative period, but were not related to any specific surgical procedures or anesthetic techniques, or to the duration of lung collapse. Pediatric anesthesiologists should be aware that pediatric RPE can occur after reexpansion of any collapsed lung and that some invasive therapies can be useful in severe cases.
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