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Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure
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The National Children's Study--a proposed plan.

Alan E Guttmacher1, Steven Hirschfeld, Francis S Collins

  • 1From the Eunice Kennedy Shriver National Institute of Child Health and Human Development (A.E.G., S.H.) and the Office of the Director, National Institutes of Health (F.S.C.) - both in Bethesda, MD.

The New England Journal of Medicine
|November 15, 2013
PubMed
Summary

The National Children's Study collects biological, environmental, and health data to understand child growth and development. This comprehensive resource aids in researching children's health outcomes.

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Area of Science:

  • Pediatric Health Research
  • Environmental Epidemiology
  • Developmental Biology

Background:

  • Understanding factors influencing child health is crucial for public health initiatives.
  • Longitudinal studies provide valuable insights into developmental trajectories.
  • Previous research highlighted the need for integrated data on children's health.

Purpose of the Study:

  • To establish a comprehensive resource for studying child growth, development, and health.
  • To investigate the interplay of biologic and environmental factors in children's health.
  • To support future research on pediatric health outcomes.

Main Methods:

  • Collection of longitudinal biologic samples.
  • Tracking of environmental exposures over time.
  • Systematic phenotypic data acquisition.

Main Results:

  • A coordinated dataset integrating biologic, environmental, and phenotypic information has been established.
  • The study is poised to yield significant findings on children's health.
  • Data infrastructure is in place for extensive analysis.

Conclusions:

  • The National Children's Study represents a significant advancement in pediatric research resources.
  • The integrated data approach is essential for understanding complex health determinants.
  • This resource will facilitate numerous studies on child health and development.