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Updated: May 6, 2026

15N CPMG Relaxation Dispersion for the Investigation of Protein Conformational Dynamics on the µs-ms Timescale
Published on: April 19, 2021
Configurational relaxation of "Van Der Waals complexes" in solution
N A Nemkovich1, A N Rubinov, Y V Zvinevich
1Stepanov Institute of Physics, Academy of Sciences of Belarus, Francisk Skarina Ave. 70, 220602, Minsk, Belarus.
Abstract:
Novel measurements on the microscopic solvation dynamics of 3-amino-N-methylphthalimide (3ANMP) in nonpolar decalin (decahydronaphthalene) solutions with small concentrations of ethanol and other polar additives have been made, using the time-dependent fluorescence Stokes shift (TDFSS) technique. It is found that the experimentally measured TDFSS slightly differs from that predicted by the theory of the generalized Smoluchowski-Vlasov equation (SVE). The essentially slower character of the TDFSS in binary solutions than given by the SVE approach may be explained by the control of the solvation behavior by the large-wavevector processes involving nearest-neighbor molecules.
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