Gender difference in patients with hepatocellular carcinoma

Area of Science:

• Hepatobiliary Medicine
• Oncology
• Cancer Research

Background:

• Hepatocellular carcinoma (HCC) is a major global cancer, predominantly affecting men.
• Understanding gender-based differences in HCC is crucial for targeted interventions.

Purpose of the Study:

• To investigate the impact of gender on clinicopathologic features and survival outcomes in hepatocellular carcinoma patients.

Main Methods:

• Retrospective analysis of 63 hepatocellular carcinoma patient records.
• Comparison of clinicopathologic characteristics and survival data between genders using SPSS.
• Statistical analysis included descriptive statistics and significance testing.

Main Results:

• Men were diagnosed at a younger age than women.
• Viral C infection was a more frequent etiology in women.
• While HCC appeared more aggressive in men, median survival did not differ significantly between genders (6.52 months).
• Lower serum albumin levels were observed in women.

Conclusions:

• Gender impacts hepatocellular carcinoma (HCC) presentation and risk factors, but not overall survival.
• Hepatocellular carcinoma (HCC) exhibits distinct gender-specific characteristics.
• Early detection and treatment strategies are vital for improving outcomes in hepatocellular carcinoma (HCC).