[Treatment of chronic gastritis patients with sodium nucleinate]

The efficacy of sodium nucleinate was studied and compared with routine agents and prednisolone in the treatment of patients afflicted with chronic gastritis. Three similar groups of 30 patients were entered into the study. The treatment with sodium nucleinate permitted the attainment of a remission in the majority of the patients. In 93.3% of the patients the remission lasted over 3 months and was marked by a significant rise of basal and stimulated gastric secretion as well as by the immunomodulating effects in the form of an augmentation of the number of T suppressors and a decrease in the number of T lymphocytes capable of inhibiting leukocyte migration on interaction with the gastric antigen.