Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Exercise and Muscle Performance01:27

Exercise and Muscle Performance

6.2K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
6.2K
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

3.5K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
3.5K
Endocrine Signaling01:45

Endocrine Signaling

53.7K
Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.
53.7K
Endocrine Signaling01:45

Endocrine Signaling

5.8K
5.8K
Structures of the Endocrine System00:59

Structures of the Endocrine System

14.0K
The intricate framework of the endocrine system encompasses a diverse array of glands, with their target tissues and organs strategically distributed throughout the body. Central to this network are the endocrine glands, specialized structures that lack ducts and release hormones directly into the interstitial fluid. Notably, the hypothalamus, a vital neuroendocrine organ situated in the brain, governs neural functions and serves as a potent source of hormonal regulation. Near the hypothalamus...
14.0K
Cellular Adaptation II: Hypertrophy01:26

Cellular Adaptation II: Hypertrophy

78
Hypertrophy is the increase in the size of individual cells, resulting in the enlargement of a tissue or organ. Unlike hyperplasia, which involves an increase in cell number, hypertrophy is characterized by an increase in cell volume. This process often occurs in response to higher functional demand or hormonal stimulation, leading to the production of more structural proteins and organelles, thereby enhancing the cells' work capacity.There are two primary types of hypertrophy:...
78

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dopaminergic neurons in the dorsal raphe nucleus may modulate social dominance in mice.

Zoological research·2025
Same author

Correction: Increased gene dosage of RFWD2 causes autistic-like behaviors and aberrant synaptic formation and function in mice.

Molecular psychiatry·2024
Same author

Increased gene dosage of RFWD2 causes autistic-like behaviors and aberrant synaptic formation and function in mice.

Molecular psychiatry·2024
Same author

[Progress on the role of Kalirin-7 in exercise intervention-mediated improvement of neurodegenerative diseases].

Sheng li xue bao : [Acta physiologica Sinica]·2023
Same author

CRF-CRFR1 system within the dorsal medial prefrontal cortex are involved in consolation deficits under acute restraint stress in mandarin voles.

Psychoneuroendocrinology·2021
Same author

Dorsal raphe nucleus to anterior cingulate cortex 5-HTergic neural circuit modulates consolation and sociability.

eLife·2021

Related Experiment Video

Updated: May 6, 2026

Measurement of Insulin- and Contraction-Stimulated Glucose Uptake in Isolated and Incubated Mature Skeletal Muscle from Mice
08:01

Measurement of Insulin- and Contraction-Stimulated Glucose Uptake in Isolated and Incubated Mature Skeletal Muscle from Mice

Published on: May 16, 2021

5.6K

[Exercise intervention in skeletal muscle endocrine function].

Zhen-Jun Tian1, Zhi-Xiong He, Meng-Xin Cai

  • 1Exercise & Cardiovascular Lab, Institute of Sports and Exercise Biology, Shaanxi Normal University, Xi'an 710062, China.

Sheng Li Ke Xue Jin Zhan [Progress in Physiology]
|November 16, 2013
PubMed
Summary
This summary is machine-generated.

Skeletal muscle acts as a secretory organ, influencing health and disease. Exercise impacts its endocrine function, offering potential for treating metabolic diseases and muscle atrophy.

More Related Videos

Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique
07:20

Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique

Published on: September 10, 2014

42.9K
Application of Chronic Stimulation to Study Contractile Activity-induced Rat Skeletal Muscle Phenotypic Adaptations
09:50

Application of Chronic Stimulation to Study Contractile Activity-induced Rat Skeletal Muscle Phenotypic Adaptations

Published on: January 25, 2018

6.3K

Related Experiment Videos

Last Updated: May 6, 2026

Measurement of Insulin- and Contraction-Stimulated Glucose Uptake in Isolated and Incubated Mature Skeletal Muscle from Mice
08:01

Measurement of Insulin- and Contraction-Stimulated Glucose Uptake in Isolated and Incubated Mature Skeletal Muscle from Mice

Published on: May 16, 2021

5.6K
Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique
07:20

Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique

Published on: September 10, 2014

42.9K
Application of Chronic Stimulation to Study Contractile Activity-induced Rat Skeletal Muscle Phenotypic Adaptations
09:50

Application of Chronic Stimulation to Study Contractile Activity-induced Rat Skeletal Muscle Phenotypic Adaptations

Published on: January 25, 2018

6.3K

Area of Science:

  • Sports Medicine
  • Endocrinology
  • Exercise Physiology

Background:

  • Skeletal muscle is increasingly recognized as a crucial endocrine organ.
  • It secretes various biologically active substances with significant physiological roles.
  • Understanding its endocrine function is vital for sports medicine and clinical applications.

Purpose of the Study:

  • To explore the mechanisms underlying exercise-induced skeletal muscle endocrine changes.
  • To identify potential biomarkers for skeletal muscle endocrine function.
  • To inform the development of exercise prescriptions for disease prevention and rehabilitation.

Main Methods:

  • This study reviews existing literature on skeletal muscle endocrine function and exercise.
  • It analyzes the impact of different exercise modes and intensities.
  • The focus is on mechanisms and potential therapeutic applications.

Main Results:

  • Exercise significantly influences skeletal muscle's endocrine function.
  • Exercise interventions show promise in managing chronic conditions like metabolic diseases (obesity, diabetes) and muscle atrophy.
  • Changes in skeletal muscle endocrine function are linked to improved health outcomes.

Conclusions:

  • Skeletal muscle's role as an endocrine organ is critical in maintaining biological homeostasis.
  • Exercise is a powerful modulator of skeletal muscle endocrine function, with therapeutic potential.
  • Further research into exercise-induced endocrine mechanisms can advance disease prevention and rehabilitation strategies.