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Anticholinergic drugs in nonallergic rhinitis
1Section of Otolaryngology--Head and Neck Surgery, The University of Chicago, Chicago, IL. rnacleri@surgery.bsd.uchicago.edu.
The World Allergy Organization Journal
|November 16, 2013
Summary
Topical anticholinergic drugs effectively treat watery anterior rhinorrhea in allergic and nonallergic rhinitis by inhibiting nasal gland secretions. These intranasal treatments offer targeted relief with minimal systemic side effects.
Area of Science:
- Otolaryngology
- Pharmacology
Background:
- The parasympathetic nervous system plays a role in allergic and nonallergic rhinitis.
- Parasympathetic stimulation activates nasal glands, causing watery secretions and anterior rhinorrhea.
Purpose of the Study:
- To review the efficacy of anticholinergic drugs in treating watery anterior rhinorrhea.
Main Methods:
- Literature review.
Main Results:
- Topical intranasal anticholinergic drugs inhibit nasal mucosal gland activation.
- These drugs effectively reduce watery secretions from parasympathetic stimulation.
- Congestion and sneezing symptoms are minimally affected; local irritation or crusting may occur.
Conclusions:
- Anticholinergic drugs are valuable for managing anterior rhinorrhea in rhinitis.
- Intranasal anticholinergics provide targeted relief for watery nasal discharge.
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