Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

891
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
891
Hypertension I: Introduction01:28

Hypertension I: Introduction

1.2K
Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
1.2K
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

1.8K
Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
1.8K
Alterations in Blood Pressure01:30

Alterations in Blood Pressure

2.1K
Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
2.1K
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

3.8K
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
3.8K
Measurement of Blood Pressure01:17

Measurement of Blood Pressure

4.0K
Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a...
4.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Standardized End Point Definitions for Clinical Trials in Thoracic Aortic Repair: A Consensus Report From the ARCH-Academic Research Consortium.

Circulation·2026
Same author

Surgical Risk and Revascularization-An Update.

Journal of the Society for Cardiovascular Angiography & Interventions·2026
Same author

Defining Exercise Hemodynamics and Function After Transcatheter Aortic Valve Replacement: The DEFINE-TAVR Prospective Study.

Journal of the Society for Cardiovascular Angiography & Interventions·2026
Same author

Enrollment of Historically Underrepresented Groups in Peripheral Arterial Disease Trials: A Systematic Review.

Journal of the Society for Cardiovascular Angiography & Interventions·2026
Same author

Treating Women With Calcified Coronary Arteries Using Intravascular Lithotripsy: Primary Results of the EMPOWER CAD Study.

Journal of the Society for Cardiovascular Angiography & Interventions·2026
Same author

Artificial intelligence-based coronary computed tomography angiography quantification of atherosclerosis burden: comparison with intravascular ultrasound in the INVICTUS Registry.

European radiology·2026
Same journal

Evaluation and analysis of renal injury in patients with advanced renal cell carcinoma receiving first-line benmelstobart plus anlotinib: results from the ETER100 study.

BMC medicine·2026
Same journal

Adverse and positive childhood experiences and suicidal ideation onset in a US pre-early adolescent cohort.

BMC medicine·2026
Same journal

Dual-drug-loaded nanohydrogel for intraoperative local application: sequential release-mediated spatiotemporal targeting of diverse secondary injury mechanisms to improve long-term prognosis in traumatic brain injury.

BMC medicine·2026
Same journal

Single-nucleus analysis of menstrual fluid highlights gene expression differences in epithelial cells of endometriosis donors.

BMC medicine·2026
Same journal

Impact of hepatotoxicity and lipid metabolism-related toxicity on survival and quality of life in patients with high-volume metastatic hormone-sensitive prostate cancer treated with rezvilutamide in the CHART trial: a post hoc analysis.

BMC medicine·2026
Same journal

The impact of public health and social measures on social contact patterns and transmission of COVID-19 in Hong Kong.

BMC medicine·2026
See all related articles

Related Experiment Video

Updated: May 6, 2026

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
07:51

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Published on: September 26, 2018

7.1K

Pre-hypertension: another 'pseudodisease'?

Pascal Meier1, Franz H Messerli, Andreas Baumbach

  • 1The Heart Hospital, University College London Hospitals UCLH, 16-18 Westmoreland Street, London W1T 7HA, UK. pascalmeier74@gmail.com.

BMC Medicine
|November 16, 2013
PubMed
Summary
This summary is machine-generated.

Pre-hypertension, defined as blood pressure between 120-140/80-90 mmHg, is a significant marker for increased cardiovascular risk. This finding prompts re-evaluation of hypertension thresholds and diagnostic criteria.

More Related Videos

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
05:51

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness

Published on: May 3, 2018

17.8K
Induction and Characterization of Pulmonary Hypertension in Mice using the Hypoxia/SU5416 Model
07:10

Induction and Characterization of Pulmonary Hypertension in Mice using the Hypoxia/SU5416 Model

Published on: June 3, 2020

9.5K

Related Experiment Videos

Last Updated: May 6, 2026

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
07:51

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Published on: September 26, 2018

7.1K
Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
05:51

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness

Published on: May 3, 2018

17.8K
Induction and Characterization of Pulmonary Hypertension in Mice using the Hypoxia/SU5416 Model
07:10

Induction and Characterization of Pulmonary Hypertension in Mice using the Hypoxia/SU5416 Model

Published on: June 3, 2020

9.5K

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Hypertension is a major cardiovascular risk factor, with diagnostic thresholds progressively lowered over time.
  • Defining the precise blood pressure level causing end-organ damage remains challenging.
  • Current trends label blood pressures from 120-140/80-90 mmHg as 'pre-hypertension'.

Purpose of the Study:

  • To evaluate the scientific justification for lowering hypertension thresholds.
  • To assess the cardiovascular risk associated with pre-hypertension.
  • To discuss the implications of redefining 'pre-hypertension' as 'hypertension'.

Main Methods:

  • Meta-analysis of existing studies on blood pressure and cardiovascular risk.
  • Review of current expert committee guidelines and scientific literature.
  • Analysis of data from Huang et al. published in BMC Medicine.

Main Results:

  • A meta-analysis indicates pre-hypertension (120-140/80-90 mmHg) is a significant marker of increased cardiovascular risk.
  • The study questions whether pre-hypertension is an independent risk factor or merely a marker.
  • Controversy exists regarding the benefits of treating pre-hypertension to reduce cardiovascular risk.

Conclusions:

  • Pre-hypertension signifies increased cardiovascular risk, necessitating careful interpretation of current hypertension guidelines.
  • Lowering the hypertension threshold to 120/80 mmHg could redefine a large 'healthy' population as patients.
  • Further research is needed to clarify the independent risk status of pre-hypertension and the efficacy of its treatment.