Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Theory of Romantic Attachment in Adulthood

Theory of Romantic Attachment in Adulthood

Attachment is a long-standing connection or bond with others. While Attachment Theory was conceived in developmental psychology to describe infant-caregiver bonding, it's been extended into adulthood to include romantic relationships.

Anxiety: Overview

Anxiety: Overview

Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.

Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu

Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu

Genetic variations significantly influence drug response through pharmacokinetics, receptor interactions, and biologic milieu modifications. Pharmacokinetic alterations impact drug metabolism and clearance, affecting efficacy and toxicity. Variants in drug-metabolizing enzymes, such as CYP2C9 and CYP2C19, alter drug activation and elimination. For example, CYP2C9 loss-of-function variants require lower warfarin doses to prevent excessive bleeding, while CYP2C19 variants reduce clopidogrel...

Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase

Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase

Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...

Human Genetics

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...

Generalized Anxiety Disorder

Generalized Anxiety Disorder

Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

New insights of platelet endocytosis and its implication for platelet function.

Frontiers in cardiovascular medicine·2024

Same author

Interactions between miRNAs and the Wnt/β-catenin signaling pathway in endometriosis.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2024

Same author

DNA barcoding for the identification and authentication of medicinal deer (Cervus sp.) products in China.

PloS one·2024

Same author

Baricitinib relieves DSS-induced ulcerative colitis in mice by suppressing the NF-κB and JAK2/STAT3 signalling pathways.

Inflammopharmacology·2024

Same author

Discovery of bioactive-chemical Q-markers of Acanthopanax sessiliflorus leaves: An integrated strategy of plant metabolomics, fingerprint and spectrum-efficacy relationship research.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences·2024

Same author

Covalent Organic Framework with 3D Ordered Channel and Multi-Functional Groups Endows Zn Anode with Superior Stability.

Nano-micro letters·2024

Search research articles

Related Experiment Video

Updated: May 1, 2026

Elevated Plus Maze for Mice

Elevated Plus Maze for Mice

Published on: December 22, 2008

The relationship between MAOA gene polymorphism and test anxiety.

Yangyang Liu¹, Zuhong Lu

¹Department of Psychology, Nanjing University, Nanjing, China.

Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies

|November 16, 2013

Summary

The mono-amine-oxidase type A gene polymorphism is linked to test anxiety in Chinese high school students. Specific genotypes, like the 4-repeat, correlate with higher anxiety levels and impact academic performance predictions.

More Related Videos

The Successive Alleys Test of Anxiety in Mice and Rats

The Successive Alleys Test of Anxiety in Mice and Rats

Published on: June 17, 2013

Use of the Open Field Maze to Measure Locomotor and Anxiety-like Behavior in Mice

Use of the Open Field Maze to Measure Locomotor and Anxiety-like Behavior in Mice

Published on: February 6, 2015

Related Experiment Videos

Last Updated: May 1, 2026

Elevated Plus Maze for Mice

Elevated Plus Maze for Mice

Published on: December 22, 2008

The Successive Alleys Test of Anxiety in Mice and Rats

The Successive Alleys Test of Anxiety in Mice and Rats

Published on: June 17, 2013

Use of the Open Field Maze to Measure Locomotor and Anxiety-like Behavior in Mice

Use of the Open Field Maze to Measure Locomotor and Anxiety-like Behavior in Mice

Published on: February 6, 2015

Area of Science:

Genetics
Psychology
Neuroscience

Background:

Test anxiety is a common issue affecting student academic performance.
Genetic factors may play a role in the development of test anxiety.
Mono-amine-oxidase type A (MAO-A) gene is involved in neurotransmitter regulation, potentially influencing behavior and emotional states.

Purpose of the Study:

To investigate the association between mono-amine-oxidase type A (MAO-A) gene polymorphism and test anxiety in Chinese high school students.
To explore whether MAO-A genotypes moderate the relationship between academic performance and test anxiety.

Main Methods:

A sample of 569 Chinese high school students was analyzed.
Genotyping for MAO-A gene polymorphism was performed.
Statistical analyses were used to assess the relationship between MAO-A genotypes, test anxiety, and academic performance.

Main Results:

Students with the 4-repeat genotype of the MAO-A gene exhibited higher levels of test anxiety.
The predictive power of academic performance on test anxiety was more pronounced in students with the 3-repeat genotype compared to those with the 4-repeat genotype.

Conclusions:

MAO-A gene polymorphism is significantly associated with test anxiety.
Specific MAO-A genotypes may influence the manifestation and impact of test anxiety on academic performance.