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Pharmacotherapy of cognitive deficits in schizophrenia
Lewis A Opler1, Alice Medalia1, Mark G Opler2
11 Department of Psychiatry, Columbia University Medical Center, New York, New York, USA.
Abstract:
While second-generation antipsychotics treat negative as well as positive symptoms, recovery for persons with schizophrenia remains elusive, in part because there are no FDA-approved medications that treat the cognitive deficits of schizophrenia (CDS). Recent work has identified agents that, when added to antipsychotics, improve cognition in schizophrenia. This work and hypothesized mechanisms of action will be reviewed.
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