Mucinous neoplasm arising in a urachal cyst: a first in the pediatric population

Area of Science:

• Pediatric Urology
• Surgical Pathology
• Developmental Biology

Background:

• Urachal anomalies stem from incomplete prenatal urachus obliteration.
• Common pediatric presentations include urachal cysts and sinuses, which can become infected.
• Malignant urachal involvement is rare in children; adenocarcinoma typically affects adults.

Observation:

• This study details an adolescent female patient.
• The patient presented with a urachal cyst.
• A low-grade mucinous neoplasm was identified within the urachal cyst.

Findings:

• A rare case of a low-grade mucinous neoplasm was found in an adolescent's urachal cyst.
• This finding is significant as primary urachal adenocarcinoma is exclusively reported in adults.
• The neoplasm's low-grade nature suggests a distinct pathway from adult adenocarcinoma.

Implications:

• This case expands the spectrum of urachal neoplasms in the pediatric population.
• It underscores the importance of thorough histopathological evaluation of urachal cysts, even in adolescents.
• Further research may elucidate the specific oncogenesis of pediatric urachal neoplasms.