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Testing which is the fitter position sensor for a cyclotron liquid target.

Osvaldo L da Costa1

  • 1Instituto de Pesquisas Energéticas e Nucleares, Av. Professor Lineu Prestes, 2242, 05508-000 São Paulo, SP, Brazil.

Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine
|November 16, 2013
PubMed
Summary

Reliability in Fluorine-18-Fluorodeoxyglucose production was improved by implementing position sensors for the Oxygen-18-labeled water target valve. This reduces production failures and ensures timely PET-CT exams.

Keywords:
CyclotronFDG-18IrradiationLiquid target

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Area of Science:

  • Nuclear Medicine
  • Radiochemistry
  • Medical Imaging

Background:

  • The production of Fluorine-18-Fluorodeoxyglucose ([(18)F]FDG) involves a complex chain with a critical 6-hour window between irradiation and PET-CT examination.
  • Failures in the production chain, such as issues with the Oxygen-18-labeled water ([(18)O]H2O) target valve, can lead to significant delays and loss of [(18)F]FDG.

Purpose of the Study:

  • To enhance the reliability of the [(18)F]FDG production chain.
  • To identify and implement a solution to prevent production losses caused by the [(18)O]H2O target valve.

Main Methods:

  • Testing of three different types of position sensors for the [(18)O]H2O target valve.
  • Evaluation of sensor performance in reducing production failures.

Main Results:

  • Successful identification of a suitable position sensor.
  • Significant reduction in the incidence of production fails related to the target valve.
  • Increased overall reliability of the [(18)F]FDG production process.

Conclusions:

  • Implementing appropriate position sensors is crucial for maintaining the integrity of the [(18)F]FDG production chain.
  • This improvement ensures a more consistent supply of [(18)F]FDG for PET-CT imaging.