Prediction and clinical relevance of pathologic patterns of injury associated with chorioamnionitis

The aim of the present study was to evaluate both prediction and clinical relevance of different patterns of injury associated with chorioamnionitis. Pathologic examination of placentas and umbilical cords were performed in 45 pregnant women who had had diagnostic amniocentesis for suspected intraamniotic infection. A positive correlation was noted between leukocyte account in amniotic fluid and the level of maternal injury (r = 0.46, p = 0.04). The levels of amniotic fluid glucose were significantly reduced in cases of fetal infection (2 mg/dL (1-16 mg/dL)) vs. (20.50 mg/dL (11-29 mg/dL)) (p = 0.03).