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Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...
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[Reactions of 4-oxo-4H-pyrido(3',2':4,5)thieno(3,2-d)-1,3-oxazines with amines].

Die Pharmazie·1992
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[Synthesis of N-(2-carboxy-thieno(2,3-b)pyridin-3-yl)amidines by means of reaction of 4-oxo-4H-pyrido(3',2':4,5)thieno(3,2-d)-1,3-oxazines with primary aliphatic amines].

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Effects of DNA binding and metal substitution on the dynamics of the GAL4 DNA-binding domain as studied by amide proton exchange.

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Related Experiment Video

Updated: May 5, 2026

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management
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Biomonitoring and environmental specimen banking.

M Paulus1, R Klein, G Wagner

  • 1Institute of Biogeography, Center of Environmental Research, Saarland University, PB15 11 50, D-66041, Saarbrücken, Germany.

Environmental Science and Pollution Research International
|November 16, 2013
PubMed
Summary

The German Environmental Specimen Banking program collects and stores environmental samples for future analysis. This ecological assessment program ensures data quality through standardized procedures and representative sampling.

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Area of Science:

  • Environmental Science
  • Ecology
  • Environmental Monitoring

Background:

  • The Federal Republic of Germany's Environmental Specimen Banking (ESB) program is crucial for ecological assessment.
  • It involves collecting specimens from representative German locations for long-term storage and analysis.

Purpose of the Study:

  • To present the ecological concept underpinning the ESB program.
  • To detail the quality assurance system for specimen collection and characterization.

Main Methods:

  • Selection of representative sampling areas and specimens.
  • Development and implementation of Standard Operating Procedures (SOPs) for sampling.
  • Application of area-specific sampling designs.

Main Results:

  • Established a framework for the ESB program based on ecological principles.
  • Defined SOPs for specimen collection and characterization.
  • Implemented quality assurance measures for accurate environmental data.

Conclusions:

  • The ESB program provides a valuable resource for ecological assessment through systematic specimen banking.
  • Standardized procedures and representative sampling are key to the program's reliability.
  • The program supports long-term environmental monitoring and research in Germany.