Related Experiment Video
Updated: May 5, 2026

Nasal Brushing Sampling and Processing Using Digital High Speed Ciliary Videomicroscopy – Adaptation for the COVID-19 Pandemic
Published on: November 7, 2020
Psychological, cognitive and maternal stress assessment in children with primary ciliary dyskinesia
Marco Carotenuto1, Maria Esposito, Francesca Di Pasquale
1Clinic, Department of Mental and Physical Health, and Preventive Medicine, Second University of Naples, Naples, Italy.
Insights
Children with Primary Ciliary Dyskinesia (PCD) exhibit more behavioral and social challenges. Mothers of children with PCD also experience higher stress levels, indicating a need for psychological support.
Area of Science:
- Pediatric Pulmonology
- Child Psychology
- Rare Diseases
Background:
- Primary Ciliary Dyskinesia (PCD) is a rare genetic disorder affecting respiratory cilia structure and function.
- Limited research exists on the psychological and behavioral aspects of PCD in children and adolescents.
- This study addresses the gap by investigating cognitive, behavioral, and parental stress in school-aged children with PCD.
Purpose of the Study:
- To evaluate the cognitive and behavioral characteristics of school-aged children diagnosed with PCD.
- To assess the levels of parental stress in mothers of children with PCD.
- To identify potential psychological support needs in the clinical management of PCD.
Main Methods:
- A cohort of 10 school-aged children with PCD and 34 healthy controls participated.
- Standardized assessments included the Wechsler Intelligence Scale for Children-III and the Child Behavior Check-List (CBCL).
- Parental stress was evaluated using the Parenting Stress Index-Short Form.
Main Results:
- Children with PCD demonstrated significantly more behavioral and social competence problems on the CBCL compared to controls, particularly in internalizing behaviors (P<0.001).
- Mothers of children with PCD reported significantly higher parental distress, impaired parent-child interaction, and total stress levels than mothers of controls (P<0.001).
Conclusions:
- Children with PCD face distinct behavioral and social challenges.
- Increased parental stress is a significant factor in families managing PCD.
- These findings underscore the necessity of integrating specific psychological support into the comprehensive care of children with PCD.
Background:
Primary ciliary dyskinesia (PCD) is a rare disorder due to structure and functional abnormalities of respiratory cilia. There are no reports on the behavioral and psychological aspects of children and adolescents with PCD. This study was undertaken to assess the cognitive and behavioural characteristics, and the parental stress of a population of school-aged children with PCD.
Methods:
Ten PCD and 34 healthy school-aged children underwent Wechsler Intelligence Scale for Children-III edition, Child Behavior Check-List questionnaire (CBCL), Parenting Stress Index-Short Form tests in order to perform a behavioural and psychological evaluation.
Results:
PCD children showed significant behavioral and social competent problems in CBCL scale than control children, in particular with regard to internalizing problems score (P<0.001). Parental distress, parent-child interaction and total stress in the mothers of PCD patients were higher than those in the controls' parents (P<0.001).
Conclusion:
Our findings pinpoint the importance of specific psychological support in the clinical management of children with PCD.
More Related Videos
05:32High-speed Video Microscopy Analysis for First-line Diagnosis of Primary Ciliary Dyskinesia
Published on: January 19, 2022
11:13Collection, Expansion, and Differentiation of Primary Human Nasal Epithelial Cell Models for Quantification of Cilia Beat Frequency
Published on: November 10, 2021
Related Concept Videos
Psychological Responses to Stress
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...