The relationship between depressive symptoms and obstructive sleep apnea in pediatric populations: a meta-analysis

Elif Yilmaz1, Karim Sedky, David S Bennett

  • 1Department of Child and Adolescent Psychiatry, Drexel University College of Medicine, Philadelphia, PA.

Insights

Children with obstructive sleep apnea (OSA) show higher depressive symptoms. Treatment with adenotonsillectomy (AT) may improve these symptoms, reducing the need for medication and enhancing overall health.

Area of Science:

  • Pediatric Sleep Medicine
  • Child Psychiatry
  • Otolaryngology

Background:

  • Obstructive sleep apnea (OSA) is increasingly linked to depressive disorders in children.
  • The precise relationship between pediatric OSA and depression remains unclear.

Purpose of the Study:

  • To investigate the association between depressive symptoms and OSA in pediatric populations.
  • To evaluate the effectiveness of adenotonsillectomy (AT) in reducing depressive symptoms in children with OSA.

Main Methods:

  • A comprehensive meta-analysis was performed on studies published up to January 2013.
  • Eleven studies (894 children with OSA, 1096 controls) examined the OSA-depression link.
  • Nine studies (379 children) assessed depressive symptoms before and after AT.

Main Results:

  • A medium, significant relationship was found between depressive symptoms and OSA (Hedges' g = 0.43, p = 0.0005).
  • Adenotonsillectomy (AT) demonstrated a medium, significant improvement in depressive symptoms post-treatment (Hedge's g = 0.41, p ≤ 0.001).

Conclusions:

  • Children with OSA exhibit elevated depressive symptoms.
  • Screening for sleep-disordered breathing is recommended for children with depressive symptoms.
  • AT may alleviate depression, decrease medication use, and improve sleep and health in children with OSA.
Abstract

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