Related Experiment Video

Updated: May 5, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

15.4K

Blood pressure impact on left ventricular geometry in chronic haemodialysis patients

K Bobocka, J Dubrava, P Slezak

    Bratislavske Lekarske Listy
    |November 19, 2013
    PubMed

    Insights

    Twenty-four-hour blood pressure significantly impacts left ventricular mass and wall thickness in chronic haemodialysis patients. However, it did not affect left ventricular ejection fraction or atrial size.

    Area of Science:

    • Nephrology
    • Cardiology
    • Hypertension Research

    Background:

    • Left ventricular hypertrophy (LVH) is a common complication in patients undergoing chronic haemodialysis.
    • LVH in this population is multifactorial, with blood pressure playing a significant role.

    Purpose of the Study:

    • To retrospectively evaluate the relationship between 24-hour ambulatory blood pressure monitoring (ABPM) and left ventricular (LV) geometry and function in chronic haemodialysis patients.

    Main Methods:

    • Fifty chronic haemodialysis patients (33 men/17 women, median age 57.5 years) were included.
    • Twenty-four-hour ABPM was performed during the short interdialytic period using the Spacelab monitor 90217.
    • Echocardiography was also conducted during the short interdialytic period.

    Main Results:

    • Left ventricular mass index showed significant correlations with 24-hour systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP).
    • SBP, DBP, MAP, and pulse pressure (PP) provided significant information for predicting relative wall thickness.
    • No significant relationships were found between 24-hour blood pressure parameters and left ventricular ejection fraction, left ventricular end-diastolic diameter, or left atrial size.

    Conclusions:

    • Twenty-four-hour blood pressure significantly influences left ventricular relative wall thickness and left ventricular mass index in chronic haemodialysis patients.
    • Left ventricular ejection fraction, left ventricular end-diastolic diameter, and left atrial size were not found to be related to 24-hour blood pressure.
    • The strongest association among diastolic parameters was observed between SBP across all three phases and the ratio of peak early to late diastolic filling velocity.
    Abstract

    More Related Videos

    Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis04:36

    Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis

    Published on: October 2, 2020

    2.3K
    Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice08:21

    Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice

    Published on: June 15, 2020

    6.2K

    Related Concept Videos

    Heart Failure II: Pathophysiology01:29

    Heart Failure II: Pathophysiology

    Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
    2.1K
    Hypertension and Regulation of Blood Pressure01:18

    Hypertension and Regulation of Blood Pressure

    Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
    3.8K
    Mitral Regurgitation I: Introduction01:20

    Mitral Regurgitation I: Introduction

    Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
    1.3K
    Hemodialysis II: Procedure and Complications01:24

    Hemodialysis II: Procedure and Complications

    DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
    2.2K
    Hemodialysis I: Introduction01:25

    Hemodialysis I: Introduction

    Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
    4.0K
    Imbalances in Cardiac Output01:26

    Imbalances in Cardiac Output

    The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
    CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
    3.3K