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Updated: May 5, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
Isolation and identification of flavonoids from Coreopsis lanceolata L. petals
Yoshiharu Okada1, Mari Okita, Yoshihiro Murai
1a Graduate School of Systems Engineering, Kinki University , Umenobe 1, Takaya, Higashi-Hiroshima 739-2116 , Japan.
Abstract:
The methanol extract of Coreopsis lanceolata L. petals was acid-hydrolysed, and 7,3',4'-trihydroxy-8-methoxyflavanone (1) and 6,3',4'-trihydroxy-7-methoxyaurone (leptosidin) (2) were successfully isolated. The structure of compound 1 is designated to flavanone based on X-ray crystallographic analysis and NMR spectroscopic analysis. Compound 1 showed high-antioxidant effects based on diphenylpicrylhydrazyl radical scavenging assay (94.3% scavenging rate) and superoxide dismutase-like activity assay (23.9% inhibition rate).

