[Fetal cytomegalovirus infection diagnosed on autopsy: a case report]

Malek Zribi1, Salwa Makni, Najla Abid

  • 1Laboratoire d'anatomie et de cytopathologie pathologiques, hôpital hospitalo-universitaire Habib Bourguiba, 3029 Sfax, Tunisie.

Annales De Pathologie
|November 19, 2013
PubMed

The cytomegalovirus (CMV) is the most common maternal-fetal transmission infectious disease. The diagnosis of this infection is rarely made on antenatal sonographic signs. Pathological examination could, in this case, make etiologic diagnosis. We report the case of a terminated pregnancy, at the term of 19 weeks of gestation, occurring in a 31-year-old woman. The sonography found a terminated pregnancy with anamnios. Histological examination of samples of fetal internal organs showed intranuclear inclusions, compatible with CMV infection. The main objective of our work is to emphasize the value of histological examination in the diagnosis of fetal death etiology. Moreover, we will discuss the benefit of antenatal screening of CMV maternal infection.