Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

FLASH radiation therapy mitigates immunogenic and pro-fibrotic transcriptomic responses in healthy lung tissue.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same author

FLASH radiotherapy induces unique immunotranscriptomic profiles compared to conventional dose-rate radiotherapy, despite identical immune infiltration and antitumor efficacy in a murine model of triple-negative breast cancer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same author

Error detection sensitivity and operational efficiency of phantom-based and phantom-less patient-specific quality assurance in proton therapy.

Zeitschrift fur medizinische Physik·2026
Same author

AI-Driven Bone and Marrow Segmentation on FLT-PET/CT: Technical Multi-organ Validation in AML and HCT.

Research square·2026
Same author

Multicentre dosimetry audit in the European randomized phase III study of neoadjuvant chemoradiotherapy using proton versus photon radiotherapy in locally advanced oesophageal cancer.

Physics and imaging in radiation oncology·2026
Same author

Telomerase Activity in Melanoma: Impact on Cancer Cell Proliferation Kinetics, Tumor Progression, and Clinical Therapeutic Strategies-A Scoping Review.

Current oncology (Toronto, Ont.)·2026

Related Experiment Video

Updated: May 5, 2026

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

15.2K

A complementary dual-modality verification for tumor tracking on a gimbaled linac system.

Kenneth Poels1, Tom Depuydt, Dirk Verellen

  • 1Department of Radiotherapy, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Belgium.

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
|November 19, 2013
PubMed
Summary

This study validated a dual-modality system for real-time tumor tracking (RTTT) verification during radiotherapy. The system accurately tracked moving tumors using orthogonal kV and MV imaging, improving treatment precision.

Keywords:
Dynamic tumor trackingIntra-fraction treatment verificationkV/MV fluoroscopy

More Related Videos

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities
07:13

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Published on: October 27, 2023

2.0K
Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
08:54

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

13.9K

Related Experiment Videos

Last Updated: May 5, 2026

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

15.2K
Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities
07:13

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Published on: October 27, 2023

2.0K
Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
08:54

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

13.9K

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Image-Guided Therapy

Background:

  • Robust intra-fraction verification is crucial for managing tumor motion during radiotherapy.
  • Dynamic tracking of moving tumors requires precise, real-time motion management.

Purpose of the Study:

  • To validate a dual-modality verification system for dynamic tumor tracking in radiotherapy.
  • To assess the system's accuracy and applicability in clinical settings.

Main Methods:

  • A dual-modality system using orthogonal kV X-ray and planar MV EPID fluoroscopy was employed.
  • Real-time tumor tracking (RTTT) utilized angular corrections with a gimbaled linac.
  • Implanted fiducials were used for target localization, with data validated against optical cameras and clinical patient data.

Main Results:

  • Phantom validation demonstrated high accuracy (<0.3mm) for both verification modalities.
  • Clinical application showed 90th percentile errors (E90) ranging from 1.92 to 3.45 mm.
  • EPID marker detection was affected by image contrast, but results agreed well with kV X-ray log data.

Conclusions:

  • Dual-modality verification was successfully implemented for RTTT.
  • The system provides detailed reporting capabilities for RTTT performance, enhancing treatment verification.