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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Kidney Transplant II: Surgical Procedure01:26

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
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Tissue Transplantation01:24

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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
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Lung transplantation in children. Specific aspects.

Antonio Moreno Galdó1, Juan Solé Montserrat, Antonio Roman Broto

  • 1Unidad de Neumología Pediátrica y Fibrosis Quística, Hospital Universitari Vall d'Hebron, Barcelona, España; Departament de Pediatria, d'Obstetricia i Ginecologia i de Medicina Preventiva, Universitat Autònoma de Barcelona, Barcelona, España.

Archivos De Bronconeumologia
|November 19, 2013
PubMed
Summary

Pediatric lung transplantation offers a viable treatment for infants and children with end-stage lung disease, significantly improving their quality of life. Survival rates at 10 years are approximately 35%, highlighting the procedure's long-term impact.

Keywords:
ChildrenCystic fibrosisFibrosis quísticaHipertensión pulmonarInterstitial pneumoniaLung transplantNeumopatías intersticialesNiñosPulmonary hypertensionTrasplante pulmonar

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Area of Science:

  • Pediatric pulmonology
  • Thoracic surgery
  • Transplantation medicine

Background:

  • Lung transplantation is an established therapy for pediatric end-stage lung disease.
  • Spain has performed 114 pediatric lung transplants since 1996, representing 3.9% of total transplants.
  • Cystic fibrosis is the primary indication in adolescents (70-80%), while interstitial lung disease and pulmonary hypertension are common in infants.

Purpose of the Study:

  • To review the outcomes and challenges of pediatric lung transplantation.
  • To highlight the indications, methods, complications, and survival rates in children undergoing lung transplants.

Main Methods:

  • Sequential double lung transplantation, often utilizing extracorporeal circulation, is the standard procedure.
  • Monitoring and follow-up present unique challenges in pediatric patients, particularly infants, due to difficulties in assessing lung function and performing biopsies.
  • Specific pediatric complications include post-transplant lymphoproliferative syndrome and increased severity of respiratory viral infections.

Main Results:

  • Pediatric lung transplantation leads to significant improvements in quality of life, with 88% of children experiencing no activity limitations after 3 years.
  • International Society for Heart & Lung Transplantation (ISHLT) registry data show 5-year survival at 54% and 10-year survival around 35%.

Conclusions:

  • Lung transplantation is a crucial therapeutic option for pediatric end-stage lung disease, comparable to adult outcomes.
  • Despite challenges in monitoring and specific complications, the procedure substantially enhances long-term quality of life for pediatric recipients.