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A rare case of persistent troponin elevation in a patient with chronic heart failure
Gonçalo Cardoso1, Carlos Aguiar, António Ventosa
1Serviço de Cardiologia, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Carnaxide, Portugal.
Insights
A young woman with hypertrophic cardiomyopathy experienced myocardial infarction without coronary artery disease. Her condition progressed to heart failure and worsening ventricular dysfunction despite treatment.
Area of Science:
- Cardiology
- Cardiovascular Medicine
- Clinical Case Study
Background:
- Hypertrophic cardiomyopathy (HCM) is a complex cardiac condition.
- Myocardial infarction (MI) in young adults without obstructive coronary artery disease is rare.
- Understanding atypical presentations of cardiovascular diseases is crucial.
Observation:
- A 28-year-old woman with diagnosed HCM experienced an MI.
- Coronary angiography revealed no significant coronary artery disease.
- Two years post-MI, she developed heart failure symptoms.
Findings:
- Persistent elevation of troponin I was noted.
- Left ventricular systolic dysfunction was diagnosed.
- Progressive worsening of ventricular dysfunction was observed over time.
Implications:
- This case highlights a potential link between HCM and myocardial infarction in the absence of traditional risk factors.
- It underscores the need for comprehensive etiological investigations in young patients with MI.
- Further research may elucidate specific pathophysiological mechanisms in HCM leading to such events.
Abstract:
We present the case of a woman diagnosed with hypertrophic cardiomyopathy who suffered a myocardial infarction when she was 28 years old, without coronary artery disease on coronary angiography. Two years later, she presented signs of heart failure and left ventricular systolic dysfunction with persistent troponin I elevation, followed by progressive worsening of ventricular dysfunction.
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