Objectively measured sleep duration and hyperglycemia in pregnancy
Sharon J Herring1, Deborah B Nelson2, Grace W Pien3
1Center for Obesity Research and Education, Department of Medicine, Temple University, Philadelphia, PA, United States; Department of Public Health, Temple University, Philadelphia, PA, United States; Department of Obstetrics, Gynecology, and Reproductive Sciences, Temple University, Philadelphia, PA, United States.
Sleep Medicine
|November 19, 2013
Summary
Shorter nighttime sleep in pregnant women is linked to a higher risk of gestational hyperglycemia. Objective sleep duration measures revealed this association, highlighting sleep
Area of Science:
- Obstetrics and Gynecology
- Sleep Medicine
- Endocrinology
Background:
- Gestational diabetes mellitus (GDM) is a significant complication of pregnancy.
- Maternal sleep patterns are increasingly recognized as potential modifiable risk factors for adverse pregnancy outcomes.
- Objective measurement of sleep provides a more accurate assessment than self-report.
Purpose of the Study:
- To determine the impact of objectively measured nighttime sleep duration on gestational glucose tolerance.
- To explore associations between daytime sleep duration, nap frequency, and maternal glycemic control.
Main Methods:
- Sixty-three pregnant women underwent wrist actigraphy for objective sleep assessment.
- Sleep data were correlated with 1-hour oral glucose tolerance test (OGTT) values.
- Logistic regression analyzed associations between sleep parameters and hyperglycemia (1-h OGTT ≥130 mg/dL).
Main Results:
- Mean nighttime sleep duration was 6.9 hours.
- Shorter nighttime sleep was inversely correlated with 1-hour OGTT values (r=-0.28, P=.03).
- Reduced nighttime sleep independently increased the risk of gestational hyperglycemia (aOR=0.2, 95% CI [0.1-0.8]).
Conclusions:
- Objective measurement of maternal sleep duration indicates that shorter nighttime sleep is associated with an elevated risk of gestational hyperglycemia.
- Daytime sleep duration and nap frequency did not show significant associations with glycemic control.
- Further large-scale prospective studies are warranted to validate these findings.
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