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N-glycosylation mutations within hepatitis B virus surface major hydrophilic region contribute mostly to immune

De-Min Yu1, Xin-Hua Li2, Vannary Mom3

  • 1Department of Infectious Disease, Institute of Infectious and Respiratory Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.

Journal of Hepatology
|November 19, 2013
PubMed
Abstract

Keywords:
AHBALTAcute Hepatitis BCHBCMIAChronic Hepatitis BHBVHBsAgHCCImmune escapeLCMHRMajor hydrophilic regionMutationN-glycosylationPCRPolymerase chain reactionaaamino acidanti-HBsanti-HBs antibodiesaspartate aminotransferasechemiluminescent microparticle enzyme immunoassayhepatitis B virushepatitis B virus surface antigenhepatocellular carcinomaliver cirrhosismajor hydrophilic regionrHBsAgrecombinant hepatitis B virus surface antigen

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